Researchers found the prevalence of SIBO in subjects with IBS was 31% and only 9% in the control group, meaning people with IBS are more likely to have SIBO. Although data varies on the prevalence of SIBO in people with IBS, a recent meta-analysis reviewed 25 case-controlled studies with more than 3,000 IBS patients and 3,000 controls without IBS. RDNs may encounter SIBO in the context of irritable bowel syndrome, as many of the symptoms overlap. People with SIBO also may experience nausea, diarrhea or constipation (which can occur depending on the type of overgrowth present). While weight loss has long been a symptom associated with SIBO, weight gain is now a recognized symptom as well.
BACTERIAL OVERGROWTH IN STOMACH FULL
Feeling full quickly, “brain fog” or fatigue, especially after eating, are other possible signs of SIBO. Abdominal pain or discomfort also is common, though intense pain is not usually associated with SIBO. Abdominal distention grows progressively worse throughout the day and is usually worst in the evening. Symptoms associated with SIBO may include abdominal distention and bloating. Additionally, the ileocecal valve keeps out unwanted microbes by blocking the connection between the colon and the small intestine.
Innate cleaning mechanisms of the small intestine include secretion of stomach acid, pancreatic excretions and the migrating motor complex, a cyclical four-stage process that occurs during fasting and includes contractions, which push residual food to the colon. Additionally, small intestine function can be altered by chronic inflammatory diseases, such as lupus, diabetes or chronic pancreatitis.Īny of these factors can disrupt the mechanisms that keep the small intestine “clean” and introduce bacteria that normally wouldn’t be there. Structural causes may include diverticula of the small intestine or fibrous bands. Medications can contribute for instance, opioids slow the bowel and anticholinergics alter gastric acid production. There are several reasons SIBO may develop: Post-surgical causes may include resections or anastomotic adhesions or strictures. SIBO is a secondary condition, meaning it occurs in response to something else, such as a disease or alteration to the small bowel. With SIBO, bacteria are displaced from the colon, increasing the number and types of microbes in the small intestine and causing excess fermentation, malabsorption or inflammation. Normally, the small intestine contains very little bacteria the concentration of microbes increases progressively down the small bowel to the colon, where approximately 38 trillion microbes live. While there is no one specific diet for people with SIBO, registered dietitian nutritionists can work with patients or clients to create individualized eating plans that help relieve symptoms.
The understanding of SIBO continues to evolve with increasing data about the human microbiome. Small intestinal bacterial overgrowth, or SIBO, is a condition caused by increased numbers of bacteria in the small intestine.
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